Citagenix
Neomem FlexPlus Collagen Membrane
SKU: NF1520
Neomem FlexPlus is a single layer collagen membrane derived from porcine peritoneum that offers strong performance with a supple touch.
We have replaced the Neomem Flexplus membrane with the substantially equivalent OsseoSeal Collagen Membrane. Osseoseal offers better pricing and superior handling!
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$129.99
$124.99
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Buy 5+ for only $114.99 each!
- Compares to BioGide
- High suture pull out strength. 3 Times that of Biogide.
- Excellent draping
- Either side up.
- Lower inflammation
- 3-4 month resorption
- Easy handling. Hydrates Quickly.
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Questions About Neomem FlexPlus Collagen Membrane
What are the benefits of Neomem Flexplus over BioGide?
Based on [this study](https://osseonews.nyc3.cdn.digitaloceanspaces.com/wp-content/uploads/2016/11/Bio-Gide-PCM-white-paper.pdf) , the benefits of Neomem FlexPlus over BioGide are as follows: Boths Sides of Neomem are Smooth. The Neomem FlexPlus does not require identification of the correct membrane side during implantation since both sides of the porcine collagen membrane are smooth. This may help to simplify use during implantation. Longer Barrier Function. The results of resorption and new collagen deposition from the more clinically relevant intra-oral rabbit implant study, demonstrated that the PCM (porcine Collagen membrane, i.e. Neomem FlexPlus) has a less varied resorption and new collagen deposition profile and appears to maintain barrier function longer than Bio-Gide® during early guided tissue regeneration (4 weeks). Lower Inflammatory Response The PCM elicits lower inflammatory and foreign body giantcell response than Bio-Gide® in vivo, suggesting that the chemical treatments of the PCM have reduced the extent of inflammation and foreign body reactions to a higher degree than Bio-Gide®. The lower degree of inflammation and foreign body response may result in enhanced tissue integration and improved wound healing in terms of minimizing scar-like tissue formation. Higher Suture Pullout Strength The higher suture pullout strength of Neomem FlexPlus provides additional assurancein terms of membrane fixation in situ.
Is the collagen cross linked or non cross linked?
Yes, the Neomem FlexPlus is cross linked both mechanically and chemically. Please see this study, which shows the benefits of the cross link in the Neomem Flexplus Membrane. To summarize the study briefly, the production and rinsing process, used to manufacture Neomem FlexPlus, removes all traces of chemical cross linking agents. In fact, Neomem FlexPlus has a lower inflammatory and giant cell response than comparable non-linked membranes. Furthermore, cross linking extends and stabilizes the resorption process. When compared to Neomem FlexPlus, the resorption of some of comparable popular non-linked membranes is irregular and rapid in certain time frames especially in the critical early stages of wound healing.
Additional Information for Neomem FlexPlus Collagen Membrane
Neomem® FlexPlus is a single layer collagen membrane derived from porcine peritoneum. Suture pullout testing has shown this membrane to be biomechanically strong yet conformability evaluations demonstrate the ability to adapt to the contour of the surgical site. Neomem® FlexPlus hydrates quickly and handling characteristics make surgical placement easy. It can be repositioned easily and placed wet or dry and with either side up. Additionally, in-vitro testing of Neomem® FlexPlus shows low tissue inflammation and foreign body giant cell response.
Compared to Bio-Gide®:
- Stronger Neomem® FlexPlus has 3 times the suture pull out strength compare to Bio-Gide® and resorption time of 3-4 months. Neomem® FlexPlus can be repositioned once placed.
- Supple Lack of memory means that Neomem® FlexPlus drapes and conforms to the defect site and since both sides are the same, it is easy to place.
- Better Initial Resorption Rate Compared to Bio-Gide®, Neomem® FlexPlus’ initial in-vivo resorption profile suggests that Neomem® FlexPlus is more stable.
- Less Inflammation In-vivo testing also demonstrates that Neomem® FlexPlus produced a lower level of early inflammation than Bio-Gide and Neomem® FlexPlus shows a lower level of giant cell response.
Download the research paper comparing BioGide to Neomem FlexPlus.
1. BioGide® is a registered trademark of Geistlich