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PentOS O Flex is a 1 mm thick osteoinductive, demineralized cortical allograft that when hydrated, becomes flexible and easily adapts to graft sites that would be difficult to treat with particulate or putty grafts. These characteristics make PentOS OI™ Flex ideally suited for the repair of shallow bone defects or bone loss.
Demineralized Flexible Cortical Sheet Features and Benefits
Common Applications include:
PentOS OI™ allografts must demonstrate all five elements of bone formation before they are released for use. Post sterilization in-vivo testing on each lot must demonstrate the presence of new bone, bone marrow, osteocytes, cartilage and chondrocytes within 28 days otherwise we can’t call it PentOS OI. In-vitro tests of PentOS OITM demonstrate levels of BMP-2 up to 19 times the native levels in the control.
The grafts are freeze-dried and sterilized using low-dose gamma irradiation to achieve a sterility assurance level (SAL) of 10-6. The grafts should be stored in ambient temperatures (59-86º F or 15-30º C) and have a shelf-life of up to five (5) years from the date of packaging. CellRight’s proprietary next-generation BioRinseTM processing technology has been proven to preserve native bone morphogenic proteins (BMP’s).
|Questions and Answers|
Yes, PentOS OI Flex can be placed over particulate graft.
In general, the use of a dental membrane is to prevent the soft tissue cell from entering the graft site prior to bone forming, and to help contain granular graft materials in place (if they are used). This is the natural role for periosteum – the separation of hard and soft tissue. As such, if there is primary closure of an intact periosteum, than this is sufficient, and there should be no need for a membrane when using PentOS OI Flex. However, without primary closure, and if the periosteum is damaged, torn or cut for vertical release, it becomes less effective as a barrier and a membrane should be used.
Yes, may cut PentOS OI Flex and fold one piece on top of the other to increase thickness.
PentOS OI Flex is 100% Bone.
PentOS OI Flex can be hydrated using the patient’s blood or with saline solution. To accelerate graft reconstitution, submerge the PentOS OI in saline for 10-30 minutes and manipulate periodically, especially for larger size grafts. Graft pliability may occur sooner than 10-30 minutes.
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