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PRF Classic Centrifuge System

Updated 2021-08-29
SKU:
DM0412
Manufacturer:
DLAB Scientific

This classic PRF Centrifuge System provides you with everything you need for the PRF protocol at a discounted price. Platelet-rich fibrin (PRF), was developed in France by Choukroun et al (2001). It is a 2nd generation platelet concentrate widely used to accelerate soft and hard tissue healing. The Centrifuge provided with our kit is easily set to match the exact specifications needed to create the PRF plugs/membranes, or injectable PRF liquid, as described in the literature**[1-5] .

PRF System package includes:

  • 1 New Centrifuge DM0412
  • 100 Red Glass Tubes 10 ml (for PRF clots/membranes)
  • 50 White Plastic Tubes 9 ml (for PRF liquid)
  • Blood collectors (24).
  • Optional PRF Instrument & Box Upgrade ($600 Extra)
  • 2-year Warranty on Centrifuge. US-based support for Centrifuge.
This PRF system is not affiliated in any manner whatsoever with Choukroun or his company Process for PRF. Read more about the system components below and in the Questions section. Feel free to call us with any questions.

SKU: DM0412

Regular Price: $999.99

What is the PRF Protocol?

The concept of PRF (Platelet Rich Fibrin) is based on the centrifugation of whole blood without anticoagulants nor bovine thrombin (nor any other gelling agent). At the end of the spin, a fibrin clot containing the majority of the platelets and white blood cells is obtained.  PRF acts as a scaffold for growth factors, which accelerate wound healing, including platelet derived growth factor (PDGF), transforming growth factor beta1 (TGF-β1), and vascular endothelial growth factor [1-5]. The expected objective of these growth factors is to accelerate the soft tissue and bone healing. Numerous international publications are available and demonstrate the effectiveness of PRF in many indications: oral surgery (implants, bone grafting, periodontal surgery, extractions, etc…), Orthoepedic, cosmetic and dermatological surgery.Today, PRF is recognized around the world as a proven technique for bone regeneration.

What is needed to create PRF ?

The technology required to produce PRF is simply an appropriate centrifuge and a set of instruments. The PRF protocol is very simple: A blood sample is taken without anticoagulant in 10-mL tubes which are immediately centrifuged at a specific RPM and time limit (the standard A-PRF TM * protocol, on the appropriate centrifuges with certain specifications, calls for 1300 rpm / 8mn, while the i-PRF TM * protocol is 700 rpm / 3mn for females and 700 rpm / 4mn for males).

According to a paper by DavidM.Dohan,DDS et al. (emphasis ours): "The absence of anticoagulant implies the activation in a few minutes of most platelets of the blood sample in contact with the tube walls and the release of the coagulation cascades. The success of this technique entirely depends on the speed of blood collection and transfer to the centrifuge. Indeed, without anticoagulant, the blood samples start to coagulate almost immediately upon contact with the tube glass, and it takes a minimum of a few minutes of centrifugation to concentrate fibrinogen in the middle and upper part of the tube. Quick handling is the only way to obtain a clinically usable PRF clot. If the duration required to collect blood and launch centrifugation is overly long, failure will occur: The fibrin will polymerize in a diffuse way in the tube and only a small blood clot without consistency will be obtained." 1

PRF Centrifuge System Components

1 (one) Centrifuge DM0412 

Easily programmed for the specification required for the PRF protocol. Easy operation with intuitive menu and easy-to-read display. See more details below.

Red 10ml Glass TubesThe red glass tubes are used for making PRF clots/membrane. Box of 100 tubes.

White Plastic Tubes, 9ml The white tubes are used for making the liquid PRF. Box of 50 tubes

Butterfly Blood Collectors: Venipuncture can be done by the Dental Surgeon (if he is trained) or by the nurse. Material: fast collector BC10. Boxes of 24 collectors.

Optional PRF Case, PRF Instrument, and PRF Box Upgrade ($600 Extra)

Our Upgraded PRF Package includes a full set of PRF Instruments, the PRF Box and a Metal Case.

Full set of 7 instruments that are essential for the PRF technique.

PRF Metal Case

New! PRF Metal case to hold all you PRF supplies.

PRF Box

The PRF Box is an extremely important instrument. It helps to: Deliver high quality membranes and constant thickness, and Recover the exudate: hydration of biomaterials.

Preserve the membranes during surgery.

Tourniquet

The tourniquet is used to perform a blood drawing.

Tube Holder

Is used to hold the tubes and let them rest after the blood drawing.

PRF Mini Tray

Used to prepare membranes, Separate the fibrin clot from the red blood cells - Cut the membranes - Fold the membranes - Make «punches»

PRF Bowl

Is used to mix the membranes cut into small pieces with biomaterials. It can also be used for the cutting: Put the membrane into the bowl and cut it with PRF scissors.

PRF Scissors

Allows to separate easily the fibrin clot from the red cells and to cut membranes into small pieces.

PRF Forceps

Is used to remove and manipulate membranes.

PRF Forceps “Giraffe”

The forceps giraffe is intended to tunneling the PRF membranes for surgical soft tissues procedures: introduce the forceps in the tunnel, open the forceps, block the PRF membranes and pull to place the membranes in the correct position.

PRF Double Spoon

Allows collecting and handling the bone filling materials in the recipient sites (alveoli, sinus, and goshawks implants).

PRF Compactor Big

Allows compacting and tamping the bone filling materials in the recipient sites (alveoli, sinus, and goshawks implants).

PRF Compactor Small

Allows compacting and tamping the bone filling materials in the recipient sites (alveoli, sinus, and goshawks implants).

PRF Pad

Is used to position the PRF membranes easily, anywhere,using the pad as a cake server. The pointed end of the pad can be introduced in the sinus.

 

 

 

DM0412 Clinical Centrifuge Features:

  • Easy programming to achieve high accuracy of speed control CPU controls all operating parameters including speed and time
  • Rotor speed can be set and displayed by RPM or G-force Operation can be timed from 30 seconds to 99 minutes or continuous running
  • Timer commences once the set speed is reached, so the separation time is more accurate
  • Gentle braking at low speeds with efficient separation
  • Parameters can be modified after the set speed is reached
  • Quick spins are possible by pressing and holding PULSE key Lid with electric lock and automatic release function saves processing time and prevents samples overheating
  • Easy operation with intuitive menu and easy-to-read backlit LCD processing display and sound alert
  • High strength plastic rotor and excellent balance technology for quiet and stable operation
  • Maintenance-free brushless DC motors to drive quickly and effortlessly accelerates the rotor to set speed
  • Automatic self-diagnosis on startup showing accumulative running time and last running parameters
  • Comes with adapters and plugs for smaller tubes
  • cTUVus approved for UL and CSA 2 YEAR WARRANTY

Specifications: 

Centrifuge DM0412
Speed 300-4500rpm, 100rpm increments
Speed Accuracy +/- 20rpm
Rotor Capacity 8 x 15ml centrifuge tubes, 12 x 10ml/7ml/5ml vacutainer
Max. RCF 2490xg
Accel / Decel 20sec / 13sec
Run Time 30secs to 99mins Timer or Continuous Operation
Motor Brushless DC motor
Display LCD
Dimensions (L) 11.0 x (W) 10 x (H) 5.5 inches (Rotor radius: 11.5cm)
Safety Devices Door interlock, Overspeed detection; Automatic internal diagnosis
Weight 14lbs
Voltage 110-240V, 50/60Hz, 3A 70W
Certification CE, UL, IVD
Advanced features Speed/RCF switch;Short-time run function; Sound-alert function

 

 

* A-PRF TM and i-PRF TM are registered trademarks of Process for PRF.

** Choukroun et al. described a technique for generating PRF by centrifuging autologous blood without an anticoagulant or other chemical agents in glass tubes 1,2,3. The yellowish fibrin clot forms in the middle of the tube a few minutes after centrifugation.

References for the PRF Centrifuge System

1. Dohan Ehrenfest DM, Choukroun J, Diss A, Dohan SL, Dohan AJJ, Mouhyi J, et al. Platelet-rich fibrin (PRF): A second- generation platelet concentrate. Part I: Technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:37-44.

2. Dohan Ehrenfest DM, Choukroun J, Diss A, Dohan AJJ, Mouhyi J, Gogly B. Platelet- rich fibrin (PRF): A second-generation platelet concentrate. Part II: Platelet- related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:45-50.

3. Choukroun J, Diss A, Simonpieri A. Platelet-rich fibrin (PRF): A second- generation platelet concentrate. Part V: Histologic evaluations of PRF effects on bone allograft maturation in sinus lift. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:299-303.

4. Dohan Ehrenfest DM, Peppo de GM, Doglioli P, Sammartino G. Slow release of growth factors and thrombospondin-1 in Choukroun’s platelet-rich fibrin (PRF): A gold standard to achieve for all surgical platelet concentrates technologies. Growth Factors. 2009;27:63-9. 4.

5. Su CY, Kuo YP, Tseng YH, CH Su, Burnouf T. In vitro release of growth factors from platelet-rich fibrin (PRF): A proposal to optimize the clinical applications of PRF. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 108:56-61.

See the Centrifuge in Action

Below you can watch a quick video showing the use of our DM0412 centrifuge to create PRF membranes.

A-PRF Demonstration Video

Video showing how to use the centrifuge to make A-PRF membranes

iPRF Demonstration Video

Video showing how to use the centrifuge for iPrf or liquid PRF.

More Information

What is the PRF Protocol?

The concept of PRF (Platelet Rich Fibrin) is based on the centrifugation of whole blood without anticoagulants nor bovine thrombin (nor any other gelling agent). At the end of the spin, a fibrin clot containing the majority of the platelets and white blood cells is obtained.  PRF acts as a scaffold for growth factors, which accelerate wound healing, including platelet derived growth factor (PDGF), transforming growth factor beta1 (TGF-β1), and vascular endothelial growth factor [1-5]. The expected objective of these growth factors is to accelerate the soft tissue and bone healing. Numerous international publications are available and demonstrate the effectiveness of PRF in many indications: oral surgery (implants, bone grafting, periodontal surgery, extractions, etc…), Orthoepedic, cosmetic and dermatological surgery.Today, PRF is recognized around the world as a proven technique for bone regeneration.

What is needed to create PRF ?

The technology required to produce PRF is simply an appropriate centrifuge and a set of instruments. The PRF protocol is very simple: A blood sample is taken without anticoagulant in 10-mL tubes which are immediately centrifuged at a specific RPM and time limit (the standard A-PRF TM * protocol, on the appropriate centrifuges with certain specifications, calls for 1300 rpm / 8mn, while the i-PRF TM * protocol is 700 rpm / 3mn for females and 700 rpm / 4mn for males).

According to a paper by DavidM.Dohan,DDS et al. (emphasis ours): "The absence of anticoagulant implies the activation in a few minutes of most platelets of the blood sample in contact with the tube walls and the release of the coagulation cascades. The success of this technique entirely depends on the speed of blood collection and transfer to the centrifuge. Indeed, without anticoagulant, the blood samples start to coagulate almost immediately upon contact with the tube glass, and it takes a minimum of a few minutes of centrifugation to concentrate fibrinogen in the middle and upper part of the tube. Quick handling is the only way to obtain a clinically usable PRF clot. If the duration required to collect blood and launch centrifugation is overly long, failure will occur: The fibrin will polymerize in a diffuse way in the tube and only a small blood clot without consistency will be obtained." 1

PRF Centrifuge System Components

1 (one) Centrifuge DM0412 

Easily programmed for the specification required for the PRF protocol. Easy operation with intuitive menu and easy-to-read display. See more details below.

Red 10ml Glass TubesThe red glass tubes are used for making PRF clots/membrane. Box of 100 tubes.

White Plastic Tubes, 9ml The white tubes are used for making the liquid PRF. Box of 50 tubes

Butterfly Blood Collectors: Venipuncture can be done by the Dental Surgeon (if he is trained) or by the nurse. Material: fast collector BC10. Boxes of 24 collectors.

Optional PRF Case, PRF Instrument, and PRF Box Upgrade ($600 Extra)

Our Upgraded PRF Package includes a full set of PRF Instruments, the PRF Box and a Metal Case.

Full set of 7 instruments that are essential for the PRF technique.

PRF Metal Case

New! PRF Metal case to hold all you PRF supplies.

PRF Box

The PRF Box is an extremely important instrument. It helps to: Deliver high quality membranes and constant thickness, and Recover the exudate: hydration of biomaterials.

Preserve the membranes during surgery.

Tourniquet

The tourniquet is used to perform a blood drawing.

Tube Holder

Is used to hold the tubes and let them rest after the blood drawing.

PRF Mini Tray

Used to prepare membranes, Separate the fibrin clot from the red blood cells - Cut the membranes - Fold the membranes - Make «punches»

PRF Bowl

Is used to mix the membranes cut into small pieces with biomaterials. It can also be used for the cutting: Put the membrane into the bowl and cut it with PRF scissors.

PRF Scissors

Allows to separate easily the fibrin clot from the red cells and to cut membranes into small pieces.

PRF Forceps

Is used to remove and manipulate membranes.

PRF Forceps “Giraffe”

The forceps giraffe is intended to tunneling the PRF membranes for surgical soft tissues procedures: introduce the forceps in the tunnel, open the forceps, block the PRF membranes and pull to place the membranes in the correct position.

PRF Double Spoon

Allows collecting and handling the bone filling materials in the recipient sites (alveoli, sinus, and goshawks implants).

PRF Compactor Big

Allows compacting and tamping the bone filling materials in the recipient sites (alveoli, sinus, and goshawks implants).

PRF Compactor Small

Allows compacting and tamping the bone filling materials in the recipient sites (alveoli, sinus, and goshawks implants).

PRF Pad

Is used to position the PRF membranes easily, anywhere,using the pad as a cake server. The pointed end of the pad can be introduced in the sinus.

 

 

 

DM0412 Clinical Centrifuge Features:

  • Easy programming to achieve high accuracy of speed control CPU controls all operating parameters including speed and time
  • Rotor speed can be set and displayed by RPM or G-force Operation can be timed from 30 seconds to 99 minutes or continuous running
  • Timer commences once the set speed is reached, so the separation time is more accurate
  • Gentle braking at low speeds with efficient separation
  • Parameters can be modified after the set speed is reached
  • Quick spins are possible by pressing and holding PULSE key Lid with electric lock and automatic release function saves processing time and prevents samples overheating
  • Easy operation with intuitive menu and easy-to-read backlit LCD processing display and sound alert
  • High strength plastic rotor and excellent balance technology for quiet and stable operation
  • Maintenance-free brushless DC motors to drive quickly and effortlessly accelerates the rotor to set speed
  • Automatic self-diagnosis on startup showing accumulative running time and last running parameters
  • Comes with adapters and plugs for smaller tubes
  • cTUVus approved for UL and CSA 2 YEAR WARRANTY

Specifications: 

Centrifuge DM0412
Speed 300-4500rpm, 100rpm increments
Speed Accuracy +/- 20rpm
Rotor Capacity 8 x 15ml centrifuge tubes, 12 x 10ml/7ml/5ml vacutainer
Max. RCF 2490xg
Accel / Decel 20sec / 13sec
Run Time 30secs to 99mins Timer or Continuous Operation
Motor Brushless DC motor
Display LCD
Dimensions (L) 11.0 x (W) 10 x (H) 5.5 inches (Rotor radius: 11.5cm)
Safety Devices Door interlock, Overspeed detection; Automatic internal diagnosis
Weight 14lbs
Voltage 110-240V, 50/60Hz, 3A 70W
Certification CE, UL, IVD
Advanced features Speed/RCF switch;Short-time run function; Sound-alert function

 

 

* A-PRF TM and i-PRF TM are registered trademarks of Process for PRF.

** Choukroun et al. described a technique for generating PRF by centrifuging autologous blood without an anticoagulant or other chemical agents in glass tubes 1,2,3. The yellowish fibrin clot forms in the middle of the tube a few minutes after centrifugation.

References for the PRF Centrifuge System

1. Dohan Ehrenfest DM, Choukroun J, Diss A, Dohan SL, Dohan AJJ, Mouhyi J, et al. Platelet-rich fibrin (PRF): A second- generation platelet concentrate. Part I: Technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:37-44.

2. Dohan Ehrenfest DM, Choukroun J, Diss A, Dohan AJJ, Mouhyi J, Gogly B. Platelet- rich fibrin (PRF): A second-generation platelet concentrate. Part II: Platelet- related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:45-50.

3. Choukroun J, Diss A, Simonpieri A. Platelet-rich fibrin (PRF): A second- generation platelet concentrate. Part V: Histologic evaluations of PRF effects on bone allograft maturation in sinus lift. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:299-303.

4. Dohan Ehrenfest DM, Peppo de GM, Doglioli P, Sammartino G. Slow release of growth factors and thrombospondin-1 in Choukroun’s platelet-rich fibrin (PRF): A gold standard to achieve for all surgical platelet concentrates technologies. Growth Factors. 2009;27:63-9. 4.

5. Su CY, Kuo YP, Tseng YH, CH Su, Burnouf T. In vitro release of growth factors from platelet-rich fibrin (PRF): A proposal to optimize the clinical applications of PRF. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 108:56-61.

Questions and Answers
Videos

See the Centrifuge in Action

Below you can watch a quick video showing the use of our DM0412 centrifuge to create PRF membranes.

A-PRF Demonstration Video

Video showing how to use the centrifuge to make A-PRF membranes

iPRF Demonstration Video

Video showing how to use the centrifuge for iPrf or liquid PRF.

Reviews
Instructions
DDSGadget Guide for:

PRF Classic Centrifuge System

Contact

20801 Biscayne Boulevard, Suite 403 Aventura, FL 33180

888-330-3964