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Neomem ECM is an extracellular matrix membrane, similar to Dynamatrix, that supports soft tissue healing and remodeling into natural tissue as the matrix is absorbed.
What is an Extracellular Matrix (ECM)?
The Extracellular Matrix (ECM) is a three-dimensional network of extracellular macromolecules, such as collagen, enzymes, and glycoproteins.(1) ECM has been found to support regrowth and healing of tissue. (2) Neomem ECM is an extracellular matrix in sheet form, made from processed porcine mesothelial tissue, with a combination of strength and tissue regeneration properties with minimal antigens. Because Neomem ECM is more than just collagen, the extra proteins support soft tissue healing and remodelling into natural tissue as the matrix is absorbed.
Key Features and Benefits of Neomem ECM
Neomem ECM Indications
Neomem ECM maintains it’s desirable structural characteristics for cellular proliferation, ideal for the following applications:
|Questions and Answers|
Full resorption of Neomem® ECM occurs after ~6 months.
The thickness of Neomem ECM is approximately 0.3 mm
Cells grow into the Neomem® ECM and it turns into host tissue. Past experiences with this product have shown that the occlusive properties persist for as long as it takes bone to form.
Cells grow into Neomem® ECM and it is well integrated within 2 weeks of implantation. Initially, these cells tend to be inflammatory cells but due to the natural tissue properties, these cells are quickly replaced by fibroblasts that begin laying down new matrix material. The new matrix gradually replaces the material in the device resulting in a regenerated tissue.
DynaMatrix® is a device made from 4 layers of a much thinner material called SiS (small intestine submucosa). Neomem® ECM is made from a single layer thicker material (from the peritoneum). This provides different handling characteristics and strengths. Both devices are considered extracellular matrices, meaning they have a variety of proteins and other biologic components.
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