Neomem Sustained Collagen Membrane


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Neomem, is the standard, sustained function, resorbable collagen membrane. It is made of Type 1 bovine collagen matrix and indicated for use in guided tissue procedures to enhance wound healing. Watch video and review Neomem cases below.

  • Derived from highly purified type I collagen fibres from bovine Achilles tendon.
  • Sustained function. Resorption Time: 26 - 38 weeks (6 - 9 months).
  • Compare to: Cytoplast® RTM*, ACE RCM6
  • Maybe sutured or tacked. Suture pullout strength between 290g and 350g.
  • Cell occlusive - retards epithelium down growth
  • Macromolecular pore size allows nutrient transfer
  • Exceptional clinical performance and easy in situ placement. Place wet or dry.
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Neomem Additional Information

Neomem Key Features and Benefits

  • Derived from highly purified type I collagen fibres from bovine Achilles tendon.
  • Higher mechanical strength for membrane stabilization in situ using either sutures or resorbable tacks. Suture pullout strength between 290g and 350g
  • Longer in vivo stability and resorption time, 26 ‑ 38 weeks, for sustained function.
  • Optimized flexibility and rigidity for better space maintenance which allows for desired tissue in-growth.
  • Either side of the Neomem can be placed towards the soft tissue or bone.
  • Easily trimmed and placed, wet or dry.
  • Gamma irradiated to sterilise/Nonpyrogenic

Neomem Cases

Case 1: Implant Placement with Simultaneous Guided Bone Regeneration
Dr. Steven Faigan, Certified Specialist in Periodontics, Kelowna, British Columbia

  • Fig. 1: Resorption of the buccal bone

  • Fig 2: Grafted atrophic ridge

  • Fig 3: Neomem Resorbable collagen membrane

  • Fig 4: Regeneration of bone

  • Fig 5: Final restoration

A 63 year old female patient presented requesting implants as a treatment modality to replace several missing posterior teeth in the lower left quadrant. Her natural teeth had been extracted 20 years earlier without replacement, resulting in a significant horizontal ridge deficiency. It was explained to the patient that although implants represented an ideal treatment option, it would be necessary to simultaneously augment the bone to allow for optimum bone integration and stability of the implants. The patient agreed to the proposed surgical and prosthetic treatment plan.

Two threaded, cylindrical, external hex Osseotite® implants (3I, Implant Innovations Inc., Palm Beach Gardens, FL) were placed into the areas of #35 and #37. With optimum implant positioning, and given the horizontal resorption of the host bone in the area, approximately 5-6 threads were exposed on the buccal surface of the implant in site #35 and 3-4 threads on the buccal surface of #37 (fig. 1).

1.0 cc of DynaGraft® II Putty (Citagenix Inc. Montreal, Quebec) was used to augment the deficient ridge and cover the exposed threads of the implants. DynaGraft® II is a bioassayed DFDBA offering the inductive capability required to achieve regeneration of vital bone. DynaGraft® II comes supplied pre-mixed in a
reverse phase medium allowing for ease of handling and accurate placement of the material. With simple finger manipulation, the material can be molded into the ideal three dimensional shape to augment the deficient area (Fig. 2). Once in position, the viscosity of DynaGraft® II reduces the risk of dislodgement during final placement, irrigation and flap closure.

A 30x40mm Neomem™ (Citagenix Inc., Montreal, Quebec) GBR resorbable membrane was placed over the graft to assist in bone graft containment and to eliminate connective tissue and epithelial invagination into the surgical site (Fig. 3).

Reapproximation of the flaps was achieved and tension free primary closure established utilizing 5-0 chromic gut sutures. A two stage submerged protocol was undertaken given the simultaneous GBR procedure.

Healing was uneventful and the implants were uncovered at 9 months. Clinical evaluation confirmed the apparent regeneration of bone on the buccal aspect of the mandible with coverage of the exposed implants threads (Fig. 4). At this time, the implants were stable and integrated and 3i’s emergence profile transitional healing abutments were placed. A soft tissue healing period followed for the next
6 weeks. Prefabricated, preparable GingiHue™ Post (3i) prosthetic abutments were inserted and the patient restored with a ceramometal cemented fixed bridge (Fig. 5).

Without the assistance of augmentation materials, endosseous implants would be limited to only those patients that presented with alveolar ridges with adequate bone volume. The predictability of guided bone regeneration techniques has increased the number of implant candidates and has facilitated prosthetically driven restorations.

Case 2: Autogenous Bone Graft Harvesting for Implant Dehiscence Defect
Dr. Doug-Seok Sohn, Associate Professor, Chair Department of Oral and Maxillofacial Surgery Daegu Catholic University Hospital, Daegu, South Korea

  • Fig. 1: Bridge in place before extractions

  • Fig 2: Osteotomies using MIS drill guide

  • Fig 3: Autogenous bone harvesting

  • Fig. 4: RotoGrafter filled with graft

  • Fig 5: Dehiscence defects around implants

  • Fig 6: Autogenous graft in place

  • Fig. 7: Neomem Collagen membrane to protect grafted bone

  • Fig 8:
    Tension free primary closure

  • Fig 9: Post-op radiograph

The patient presented with a fourunit bridge that was supported by the second premolar and third molar, which were both unsalvageable (Fig. 1). The bridge was removed, the two teeth were extracted and the site was allowed to heal for six weeks. In this case, no grafting material was used at the time of extraction.

The treatment plan included three endosseous implants to be placed posteriorly to the first premolar to support a fixed prosthesis. At the time of the implant placement surgery, significant horizontal bone loss was observed. Implant sites for three MIS implants were prepared using the MIS drill guide (Fig. 2). Following this and prior to implant placement, an autogenous bone graft was harvested at the implant surgical site using the RotoGrafter™. It was attached to a 16:1 contra-angle handpiece and the drill speed was set to 1000 RPM. The Rotografter was used to perforate the buccal plate inferior as well as distal to the implant sites, thus allowing bone to be collected without compromising implant placement (Fig. 3-5).

Upon insertion of the three root form implants, dehiscence defects were noted ranging from 2mm to 5mm buccally and coronally around the implants. The 100% autogenous bone graft collected from the RotoGrafter was placed in the deficient areas (Fig. 6). A resorbable collagen membrane (Neomem, Citagenix Inc.) was used to cover the graft site and a tension free suture technique was employed to achieve primary closure (Fig. 7-8).

*Cytoplast® is a registered trademark of Osteogenics Biomedical, Inc.

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Neomem with a Raptos Graft

Demonstration on a model, of a basic bone graft using a Raptos allograft syringe and standard Neomem resorbable collagen membrane.

Review of all Neomem Membranes

Confused by which Neomem membrane to choose? This video will help clear about any questions you might have. It compares all 3 membranes, Neomem, Neomem Flexplus and Neomem ECM.

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Recent reviews


5 out of 5 stars

Neomem has been my membrane of choice for many years. The performance has been excellent and handling is easy (either side of the Neomem can be placed towards the soft tissue or bone).