bioXen Bovine Bone Graft

Ousia bioXEN Bovine Cancellous Bone Granules addresses the need for a biocompatible, safe, and effective osteoconductive matrix. This matrix, combined with a well vascularized site and containment of the bioXEN particulate, provides a scaffold for the natural process of bone development. The inclusion of barrier membranes allows for site protection from undesired soft tissue ingrowth.

An Osteoconductive Matrix

Ousia bioXEN is a naturally sourced anorganic bovine bone mineral, produced by the removal organic material from bovine bone. The unique manufacturing process of bioXEN results in a bone grafting particulate with the crystalline structure of carbonate apatite, which is a structure similar to intact human bone. In addition, the manufacturing process for bioXEN allows for a combination of a porous structure for vascular access with a roughened surface that is favorable to cell adhesion and subsequent bone matrix deposition.

Ousia bioXEN allows the clinician to have available a safe and biocompatible osteoconductive matrix that can be used for new bone formation in defects.

Proven Results

bioXEN and BioOss® sections taken at 2 months, show residual implant material present within the defects. The histology images shown below refer to new bone in apposition to the bioXEN or Bio-Oss® bone mineral matrix. New bone (green) can also be seen adjacent to the mineral showing evidence of ongoing bone formation in the defect area.

In vivo studies comparing Ousia bioXEN and Bio-Oss®, show the similarities in performance of these products. In this study, there were no significant differences between the two products. (2)

Reconstruction of the alveolar ridgePeriodontal defectsExtraction socketsSinus elevationsProcedures involving guided bone or guided tissue regeneration

1. Bio-Oss® is a registered trademark of Geistlich, Wolhusen, Switzerland.
2. Data on file.